Zebrafish Developmental Staging Series
| Period | Stage | Developmental Landmarks |
|---|---|---|
| Cleavage (0.75 – 2.25 h) | 32-cell | 4 X 8 array of blastomeres |
| 64-cell | 3 regular tiers of blastomeres | |
| Blastula (2.25 – 5.25 h) | 128-cell | 5 blastomere tiers; cleavage planes irregular |
| 256-cell | 7 blastomere tiers |
How does the zebrafish develop from the one cell to the many cells that make up the larva?
Zebrafish develop rapidly from a one-cell zygote that sits on top of a large yolk cell. Gastrulation begins approximately 6 h post fertilization, hatching at 2 days as a free-swimming larvae. Zebrafish reach sexual maturity around 3 months of age and can live for up to 5 years.
What is the size of a zebrafish embryo?
egg diameter
| Value | 0.7 mm |
|---|---|
| Reference | Kimmel et al., 1995. Stages of Embryonic Development of the Zebrafish. Developmental Dynamics 203(3):253-310 |
| Comments | see source for more details on zebrafish development |
| Entered by | Phil Mongiovi |
| ID | 101661 |
What are the stages in animal embryonic development?
They occur via four essential stages in early animal development: Fertilization: the process of a single sperm cell combining with single egg cell to form a zygote. Cleavage: rapid, multiple rounds of mitotic cell division where the overall size of the embryo does not increase.
How are the developing zebrafish cells different from each other?
Yet, the cells develop different characteristics at different locations in the embryo. The organism begins as a single cell (fertilized egg) that divides successively to produce many cells, with each parent cell passing identical genetic material (two variants of each chromosome pair) to both daughter cells.
What is the blastula stage of embryonic development?
An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence.
What are the stages of embryo?
The process of prenatal development occurs in three main stages. The first two weeks after conception are known as the germinal stage, the third through the eighth week is known as the embryonic period, and the time from the ninth week until birth is known as the fetal period.
Is the zebrafish a good model for embryological development studies?
Introduction Zebrafish or zebra danio (danio rerio) are seen as one of the latest “models” for vertebrate embryological development studies. These embryos have the great advantage that they develop as “see through” embryos, that is, all internal development can be clearly observed from the outside in the living embryo.
What can we learn from zebrafish mutations of ovarian development?
Dozens of genes related to ovarian development have been knocked out in zebrafish in recent years. Much new information and perspectives on the molecular mechanism of ovarian development have been obtained from these mutant zebrafish. Some findings have challenged conventional views.
What is pronephros in zebrafish?
Some Recent Findings. Zebrafish Pronephros Development “The pronephros is the first kidney type to form in vertebrate embryos. The first step of pronephrogenesis in the zebrafish is the formation of the intermediate mesoderm during gastrulation, which occurs in response to secreted morphogens such as BMPs and Nodals.
Can zebrafish be used for targeted gene knockout research in ovarian cancer?
Recently, with the advent of genome editing techniques, targeted gene knockout research can be carried out in many species. Zebrafish has emerged as an excellent model system to study the control of ovarian development. Dozens of genes related to ovarian development have been knocked out in zebrafish in recent years.
