The overall effect of calcitonin is to lower the concentration of calcium in the blood when it rises above the normal value. It also lowers the concentration of phosphorus in the blood when levels exceed normal. Calcitonin acts to decrease serum calcium concentrations in several ways.
What disease is caused by calcitonin?
If too much calcitonin is found in the blood, it may be a sign of a type of thyroid cancer called medullary thyroid cancer (MTC). High levels may also be a sign of other thyroid diseases that can put you at a higher risk for getting MTC.
What stimulates release of parathyroid hormone?
Parathyroid hormone is mainly controlled by the negative feedback of calcium levels in the blood to the parathyroid glands. Low calcium levels in the blood stimulate parathyroid hormone secretion, whereas high calcium levels in the blood prevent the release of parathyroid hormone.
What causes goiter?
Goiter Causes The most common cause of a goiter worldwide is a lack of iodine in the diet. In the United States, where iodized salt is readily available, goiters may be a result of the over- or underproduction of the thyroid hormone or the presence of nodules in the thyroid itself.
What causes cretinism and goiter?
Iodine deficiency is well known as cause of cretinism in fetus and newborn, characterized by low birth weight, short stature, mental retardation, deaf, and/or mutism. Iodine deficiency in later period of life causes goiter commonly seen in low iodine intake region.
What causes calcium to leach from bones?
When one of the parathyroid glands is overactive (hyperparathyroidism) the parathyroid tumor makes too much PTH hormone which then causes our bones to release calcium constantly into the blood stream. This causes the bones to lose their density and hardness (it is the calcium that makes them hard).
