Focal segmental glomerulosclerosis, or FSGS, can be caused by a variety of conditions, like diabetes, sickle cell disease, other kidney diseases, and obesity. It can also be caused by an infection and drug toxicity.
Is FSGS the same as nephrotic syndrome?
FSGS is a rare disease that attacks the kidney’s filtering units (glomeruli) and causes serious scarring, leading to permanent kidney damage and even kidney failure. FSGS is one of the causes of a serious condition known as Nephrotic Syndrome.
Can you live a normal life with FSGS?
Can I lead a normal life with FSGS? The condition itself does not cause any specific symptoms or pain. Fluid retention or kidney failure may affect day-to-day life. Most patients with this disease, however, lead normal lives and go work, have children and so on.
How do you treat FSGS?
FSGS treatment
- An angiotensin-converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB) to lower your blood pressure and reduce protein in your urine.
- High cholesterol medication.
- Diuretic medications to help excrete salt and water, which can improve blood pressure and swelling.
Can FSGS be treated?
The treatment options for relapsing FSGS are similar to those used for relapsing minimal-change disease. These include another course of steroids, the use of cytotoxic agents (cyclophosphamide, chlorambucil, or MMF) or calcineurin inhibitors (cyclosporine A [CSA] or tacrolimus).
What is the life expectancy of someone with FSGS?
The Kidney Disease: Improving Global Outcomes Glomerulonephritis Work Group reports that children with FSGS progressing to ESRD have a significantly reduced life expectancy of approximately 19 years following the start of dialysis and live an average of 40 years after kidney transplantation.
What is the survival rate of FSGS?
Patients entering remission have an excellent prognosis, with a 10-year renal survival rate of >90%, compared with approximately <35% in patients not attaining remission. As shown by Troyanov et al.,26 even a partial remission portends a good prognosis, with a 10-year renal survival rate of approximately 75%.
Are eggs good for kidney patients?
Although egg yolks are very nutritious, they contain high amounts of phosphorus, making egg whites a better choice for people following a renal diet. Egg whites provide a high quality, kidney-friendly source of protein.
Does having FSGS put me at risk for other conditions?
Having FSGS does NOT put you at risk for any of these conditions you do not already have. However, having family members with FSGS does increase your chances of developing it yourself. Also, the disease is twice as common in blacks than in whites.
What is the prevalence of FSGS in the US?
In 2004, Kitiyakara et al. ( 18) noted a two-decade-long trend of increasing ESRD attributed to FSGS in the United States. Incident rates, expressed as patients per million, were 6.8 in blacks, 3.7 in Hispanics, and 1.9 in whites.
Can FSGS be divided into primary and secondary forms?
D’Agati et al. ( 20) initially proposed that FSGS be divided into primary (idiopathic) and secondary forms.
What are The racial predilections of FSGS in the US?
In 2004, Kitiyakara et al. ( 18) noted a two-decade-long trend of increasing ESRD attributed to FSGS in the United States. Incident rates, expressed as patients per million, were 6.8 in blacks, 3.7 in Hispanics, and 1.9 in whites. The rise in FSGS prevalence has been observed in other populations as well.
