Glomerular disease may be caused by an infection or a drug that is harmful to your kidneys. In other cases, it may be caused by a disease that affects the entire body, like diabetes or lupus. Many different diseases can cause swelling (inflammation) or scarring (sclerosis) of the glomerulus.
What are three risk factors for glomerulonephritis?
Some of the problems that can lead to glomerulonephritis include:
- High blood pressure.
- Diabetes.
- Cancer.
- Strep throat.
- Regularly taking more than the recommended dose of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, aspirin or naproxen.
- Bacterial infection of your heart.
What are the symptoms of glomerular disease?
What are the symptoms of glomerular disease?
- albuminuria: large amounts of protein in the urine.
- hematuria: blood in the urine.
- reduced glomerular filtration rate: inefficient filtering of wastes from the blood.
- hypoproteinemia: low blood protein.
- edema: swelling in parts of the body.
What drugs can cause glomerulonephritis?
Drugs Associated with Nephrotoxicity
| Drug class/drug(s) | Pathophysiologic mechanism of renal injury |
|---|---|
| Allopurinol (Zyloprim) | Acute interstitial nephritis |
| Gold therapy | Glomerulonephritis |
| Haloperidol (Haldol) | Rhabdomyolysis |
| Pamidronate (Aredia) | Glomerulonephritis |
Which of the following conditions most commonly causes acute glomerulonephritis?
The most common infectious cause of acute GN has historically been infection by Streptococcus species (ie, group A, beta-hemolytic). Two types have been described, involving different serotypes: Serotype 12 – Poststreptococcal nephritis due to an upper respiratory infection, occurring primarily in the winter months.
What are the 2 major causes of glomerular injury?
Causes of glomerular disease include:
- Infection or a medication or chemical that is harmful to your kidney.
- Diseases that affect the entire body, including the kidneys.
- Diseases that cause swelling or scarring of the nephron or glomerulus.
- An unknown cause.
What causes hypertension in glomerulonephritis?
Patients with acute GN have hypertension primarily due to sodium retention leading to fluid overload, as evidenced by suppression of the renin-angiotensin-aldosterone (RAAS) system.
Which is the main complication of glomerulonephritis?
Glomerulonephritis can damage your kidneys so that they lose their filtering ability. As a result, dangerous levels of fluid, electrolytes and waste build up in your body. Possible complications of glomerulonephritis include: Acute kidney failure.
What medications affect creatinine?
High Creatinine Levels on Your Blood Test? Taking These 4 Drugs Can Cause a False Alarm
- 1) Sulfamethoxazole / trimethoprim (Bactrim / Septra)
- 2) Acid blockers — cimetidine (Tagamet) & ranitidine (Zantac)
- 3) Cephalosporin antibiotics.
- 4) Fenofibrate (Tricor)
Is glomerulonephritis curable?
Some types of glomerulonephritis can be cured, others can be stopped, and most can at least be slowed down.
