Normal Results HbA: 95% to 98% (0.95 to 0.98) HbA2: 2% to 3% (0.02 to 0.03)
What is a normal hemoglobin electrophoresis result?
Normal Results In adults, these are normal percentages of different hemoglobin molecules: HbA: 95% to 98% (0.95 to 0.98) HbA2: 2% to 3% (0.02 to 0.03) HbE: Absent.
What does HbA2 indicate?
Hemoglobin A2 (HbA2) is a normal variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2) and is found at low levels in normal human blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.
What does low HbA2 mean?
Low Hb A2 percentages were found in iron-deficiency anemia, hereditary persistance of fetal hemoglobin, and Hb H disease. In iron-deficiency anemia, the lowest levels of Hb A2 were observed in association with the most severe anemia.
What if HbA2 is low?
How do you read Hemoglobinopathy results?
Hemoglobin F (Hb F): Hb F may be elevated in several disorders, such as beta thalassemia and sickle cell anemia. Hemoglobin H (Hb H)…What does the test result mean?
| Results Seen | Condition | Genes |
|---|---|---|
| Majority Hb C No Hb A | Hemoglobin C disease | Two gene copies for Hb C (homozygous) |
What is immunoelectrophoresis used for?
The method is mainly used clinically to determine the blood levels of immunoglobulins, and aids in the diagnosis and evaluation of the therapeutic response in many disease states affecting the immune system and also in the diagnosis of multiple myeloma. A similar technique is called rocket immunoelectrophoresis.
What happens when HbA2 is low?
What is HbA2 E?
In this study, we established the normal ranges of haemoglobin A2 (HbA2) and haemoglobin F (HbF) levels for normal individuals using this system and also the HbA2 level in beta thalassaemia and haemoglobin E (HbE) individuals.
What is a HBA2 test used for?
HbA2 Haemoglobin A2 Test. Haemoglobin A2 is useful for helping the laboratory to diagnose some genetic mutations of haemoglobin, depending on the type of genetic mutation that has been inherited the level of A2 will rise or fall.
What is the meaning of HB electrophoresis?
Hemoglobin electrophoresis measures the levels of the different types of this protein in the blood. Hb electrophoresis; Hgb electrophoresis; Electrophoresis – hemoglobin; Thallasemia – electrophoresis; Sickle cell – electrophoresis; Hemoglobinopathy – electrophoresis
What is the reference range for a hemoglobin electrophoresis test?
Hemoglobin electrophoresis is used as a screening test to identify variant and abnormal hemoglobins, including hemoglobin A1 (HbA1), hemoglobin A2 (HbA2), hemoglobin F (HbF; fetal hemoglobin), hemoglobin C (HbC), and hemoglobin S (HbS). The reference ranges are as follows: HbA1: 95%-98%. HbA2: 1.5%-3.5%.
What is the true HBA2 level for HbE heterozygotes?
The HbA2 level for HbE heterozygotes was 3.58% (SD 0.44%), which was significantly higher than normal (p < 0.001) but lower than that of beta-thalassaemia heterozygotes (p < 0.001) and the true HbE level was 24.28% (SD 3.38%).
