Traumatic panniculitis refers to changes in the subcutaneous fat related to physical or chemical agents. The clinical picture of traumatic panniculitis is nonspecific. Cutaneous lesions are indurated, warm, red, subcutaneous plaques or nodules not necessary related to the intensity of the injury.
What causes lobular panniculitis?
Causes of Panniculitis Infections (viral or bacterial) Inflammatory diseases, like Crohn’s disease or ulcerative colitis. Specific medicines, like certain types of antibiotics or contraceptive pills. Sarcoidosis, a rare disease that causes your cells to create clumps called granulomas in the skin or lungs.
How is lobular panniculitis treated?
Treatment of panniculitis includes:
- Treat the underlying cause, if known (eg, stop a medication, treat an infection)
- Rest and elevate the affected area.
- Compression hosiery (18–25 mm Hg pressure if these can be tolerated)
- Pain relief using anti-inflammatory medications such as aspirin, ibuprofen or diclofenac.
What causes lupus panniculitis?
Lupus panniculitis is thought to be caused by an autoimmune reaction in the deep dermis and adipose tissue. The first stage of lupus panniculitis is active inflammation with painful nodules, followed by the second stage of subcutaneous atrophy that can be cosmetically disfiguring.
What is cold panniculitis?
Cold panniculitis (CP) is an acute, nodular, erythematous eruption usually limited to areas exposed to the cold. Cold panniculitis results from a cold injury to adipose tissue.
What is focal fat necrosis?
Fat necrosis is a benign (non-cancerous) breast condition that happens when an area of the fatty breast tissue is damaged, usually as a result of injury to the breast. It can also happen after breast surgery or radiation treatment. Fat necrosis is more common in women with very large breasts.
Why is panniculitis so painful?
Panniculitis is a group of conditions that cause painful bumps, or nodules, to form under your skin, often on your legs and feet. These bumps create inflammation in the fat layer under your skin. This layer is called the panniculus, or subcutaneous fat layer.
What are the symptoms of mesenteric panniculitis?
Clinical symptoms of mesenteric panniculitis are highly variable. Some individuals have few or no noticeable symptoms; others may be greatly affected by a variety of complaints including abdominal pain, nausea/vomiting, bloating, early satiety, loss of appetite and diarrhea or constipation.
Is mesenteric panniculitis painful?
The most common symptom of mesenteric panniculitis is abdominal pain. The pain is generally located in the middle portion of the abdomen but can be present in other areas of the abdomen or pelvis as well.
Is panniculitis an autoimmune disease?
Evidence suggests that mesenteric panniculitis is an autoimmune disorder.
Is panniculitis serious?
Mesenteric panniculitis typically isn’t life-threatening. It may go away on its own, or it could develop into a severe disease. But while the inflammation is there, it can cause pain and other symptoms that interfere with your life. Your doctor can give you medicine to manage this inflammation and control symptoms.
How is gouty panniculitis characterized in patients with gout?
Gouty panniculitis is a rare manifestation of gout. It is characterized clinically by indurated, erythematous, or ulcerated subcutaneous nodules. Histologic confirmation is achieved by identification of tophaceous crystal deposition in the lobular subcutaneous tissue [ 1, 2 ].
What is the history of panniculitis?
The history of the eponym began in 1892 when Pfeifer first described the skin condition now known as Weber-Christian disease, or idiopathic lobular panniculitis. In 1925, Weber further depicted the syndrome, and Christian emphasized the significance of fever as part of the syndrome.
How is Weber-Christian disease differentiated from other panniculitis?
Increasing study and diagnostic sophistication have differentiated Weber-Christian disease from diseases such as lupus panniculitis, factitial panniculitis, panniculitis associated with pancreatic disease, histiocytic cytophagic panniculitis, and alpha1-antitrypsin deficiency panniculitis. [ 6]
How are the types of panniculitis (hives) classified?
Most types of panniculitis have both septal inflammation (early) and lobular inflammation (later). Further classification is based on whether or not there is subcutaneous vasculitis, and the type of inflammation noted ( neutrophils, lymphocytes, histiocytes, granulomas ).
